Invention Grant
- Patent Title: 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin
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Application No.: US15520770Application Date: 2015-10-22
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Publication No.: US10201617B2Publication Date: 2019-02-12
- Inventor: Qun Sun
- Applicant: Zhuhai Beihai Biotech Co., Ltd.
- Applicant Address: CN Zhuhai
- Assignee: Zhuhai Beihai Biotech Co., Ltd.
- Current Assignee: Zhuhai Beihai Biotech Co., Ltd.
- Current Assignee Address: CN Zhuhai
- Agency: Fish & Richardson P.C.
- Agent Vasily A. Ignatenko
- International Application: PCT/US2015/056900 WO 20151022
- International Announcement: WO2016/065139 WO 20160428
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61K47/64 ; A61K9/00 ; A61K9/08 ; A61K9/19 ; A61K31/454
Abstract:
The present disclosure provides derivatives of 3-substituted piperidine-2, 6-diones, non-covalently bound complexes with serum albumin, pharmaceutical compositions of the same, and methods of use thereof. The non-covalently bound complexes are significantly more water-soluble than the parent compounds, and are useful for the treatment of a cancer, such as multiple myeloma.
Public/Granted literature
- US20170319708A1 3-Substituted Piperidine-2, 6-Diones and Non-Covalent Complexes with Albumin Public/Granted day:2017-11-09
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