Invention Grant
- Patent Title: Methods of promoting wound healing using CRM1 inhibitors
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Application No.: US14777302Application Date: 2014-03-14
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Publication No.: US10202366B2Publication Date: 2019-02-12
- Inventor: Tami Rashal , Dilara McCauley , Sharon Shacham , Erkan Baloglu
- Applicant: Karyopharm Therapeutics Inc.
- Applicant Address: US MA Newton
- Assignee: Karyopharm Therapeutics Inc.
- Current Assignee: Karyopharm Therapeutics Inc.
- Current Assignee Address: US MA Newton
- Agency: Foley Hoag LLP
- International Application: PCT/US2014/029322 WO 20140314
- International Announcement: WO2014/144772 WO 20140918
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; A61K31/4196 ; C07D231/12 ; C07D233/64 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D403/04 ; C07D403/06 ; C07D403/14 ; C07D405/12 ; C07D409/04 ; C07D409/12 ; C07D413/06 ; C07D413/12 ; C07D417/04 ; C07D417/06 ; C07D417/12 ; C07D249/08 ; C07D257/04 ; C07D487/10 ; C07D207/325 ; C07D207/33 ; C07D213/50 ; A61K31/41
Abstract:
The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein Ring A, X, R1, R2 and n are as defined and described herein, in a method for promoting wound healing in a subject.
Public/Granted literature
- US20160304500A1 Methods of Promoting Wound Healing Using CRM1 Inhibitors Public/Granted day:2016-10-20
Information query
