Invention Grant
- Patent Title: Heterocyclic compounds and methods of use thereof
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Application No.: US15317864Application Date: 2015-06-12
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Publication No.: US10202367B2Publication Date: 2019-02-12
- Inventor: Tsanyang Liang , Zongyi Hu , Juan Jose Marugan , Noel Terrence Southall , Shanshan He , Xin Hu , Jingbo Xiao , Marc Ferrer , Wei Zheng , Kevin J. Frankowski , Frank J. Schoenen , Kelin Li
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services , University of Kansas
- Applicant Address: US DC Washington US KS Lawrence
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,University of Kansas
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,University of Kansas
- Current Assignee Address: US DC Washington US KS Lawrence
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2015/035658 WO 20150612
- International Announcement: WO2015/192077 WO 20151217
- Main IPC: C07D413/14
- IPC: C07D413/14 ; A61K31/4545 ; C07D417/14 ; C07D471/08 ; A61K31/496 ; A61K31/5377 ; C07D413/06 ; A61K31/4178 ; A61K31/454 ; A61K31/7056 ; A61K31/7068 ; A61K38/07 ; A61K38/13 ; A61K38/21
Abstract:
Disclosed are compounds of formula (I), formula (II), and formula (III): wherein Ar, R1, A, and X are as defined in the specification. These compounds are antiviral agents and are contemplated for use in the treatment of viral infections, for example, hepatitis C. These compounds are also contemplated for use in treating or preventing cancers.
Public/Granted literature
- US20170114053A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF Public/Granted day:2017-04-27
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