Invention Grant
- Patent Title: Anti-cancer compounds targeting Ral GTPases and methods of using the same
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Application No.: US15324629Application Date: 2015-07-10
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Publication No.: US10202397B2Publication Date: 2019-02-12
- Inventor: Dan Theodorescu , Michael Fitzpatrick Wempe , David Ross , Chao Yan , Phillip Reigan
- Applicant: THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Sheridan Ross P.C.
- International Application: PCT/US2015/040021 WO 20150710
- International Announcement: WO2016/007905 WO 20160114
- Main IPC: C07D491/052
- IPC: C07D491/052 ; A61K31/4162 ; A61K45/06
Abstract:
Methods of inhibiting the growth or metastasis of a cancer in a subject by inhibiting a Ral GTPase in the subject, and small molecule inhibitors of Ral GTPases useful in the methods of the invention. Pharmaceutical compositions containing the compounds of the invention, and methods of using the same.
Public/Granted literature
- US20170204112A1 ANTI-CANCER COMPOUNDS TARGETING RAL GTPASES AND METHODS OF USING THE SAME Public/Granted day:2017-07-20
Information query
