Invention Grant
- Patent Title: Methods of treating and preventing Staphylococcus aureus infections and associated conditions
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Application No.: US15699345Application Date: 2017-09-08
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Publication No.: US10202440B2Publication Date: 2019-02-12
- Inventor: Victor J. Torres , Francis Alonzo, III
- Applicant: New York University
- Applicant Address: US NY New York
- Assignee: New York University
- Current Assignee: New York University
- Current Assignee Address: US NY New York
- Agency: LeClairRyan PLLC
- Main IPC: C07K16/12
- IPC: C07K16/12 ; A61K39/40 ; A61K39/085 ; A61K31/7088 ; A61K31/724 ; G01N33/50 ; G01N33/569 ; A61K38/16 ; A61K39/00
Abstract:
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin E and/or D proteins or polypeptides and anti-leukocidin E and/or D antibodies. The invention further relates to methods of identifying inhibitors of LukE/D cytotoxicity and inhibitors of LukE/D-leukocyte binding.
Public/Granted literature
- US20180057571A1 METHODS OF TREATING AND PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS AND ASSOCIATED CONDITIONS Public/Granted day:2018-03-01
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