Invention Grant
- Patent Title: AAV-based treatment of cholesterol-related disorders
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Application No.: US14995699Application Date: 2016-01-14
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Publication No.: US10202600B2Publication Date: 2019-02-12
- Inventor: Guangping Gao , Phillip D. Zamore , Jun Xie
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K48/00 ; C12Q1/68 ; C12N15/86 ; C12N7/00 ; C12Q1/6897
Abstract:
The invention in some aspects relates to methods and compositions for assessing the effectiveness of miRNA inhibitors. In other aspects of the invention, methods and compositions for treating cholesterol related disorders are provided. In one aspect of the invention, miRNA inhibitors against miR-122 and rAAV-based compositions comprising the same are provided.
Public/Granted literature
- US20160208257A1 AAV-BASED TREATMENT OF CHOLESTEROL-RELATED DISORDERS Public/Granted day:2016-07-21
Information query
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