Invention Grant
- Patent Title: Complex containing oligonucleotide having immunopotentiating activity and use thereof
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Application No.: US15022856Application Date: 2014-09-19
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Publication No.: US10202606B2Publication Date: 2019-02-12
- Inventor: Ken Ishii , Kouji Kobiyama , Taiki Aoshi , Fumihiko Takeshita , Yuji Kasuya , Takako Niwa , Makoto Koizumi
- Applicant: NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION , DAIICHI SANKYO COMPANY, LIMITED
- Applicant Address: JP Ibaraki JP Tokyo
- Assignee: NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION,DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee: NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION,DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee Address: JP Ibaraki JP Tokyo
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2013-196206 20130920
- International Application: PCT/JP2014/074835 WO 20140919
- International Announcement: WO2015/041318 WO 20150326
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K39/00 ; A61K39/12 ; A61K39/39 ; C07H21/04 ; C08B37/00 ; A61K31/713 ; A61K39/145 ; A61K39/155 ; C12N15/117 ; A61K31/7125

Abstract:
The present invention provides an oligodeoxynucleotide containing humanized K type CpG oligodeoxynucleotide and poly deoxyadenylate, wherein the poly deoxyadenylate is placed on the 3′-side of the humanized K type CpG oligodeoxynucleotide. In addition, the present invention provides a complex containing the aforementioned oligodeoxynucleotide and β-1,3-glucan.
Public/Granted literature
- US20160208260A1 COMPLEX CONTAINING OLIGONUCLEOTIDE HAVING IMMUNOPOTENTIATING ACTIVITY AND USE THEREOF Public/Granted day:2016-07-21
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