Invention Grant
- Patent Title: Recombinant cell, and method for producing 1,4-butanediol
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Application No.: US14760793Application Date: 2014-01-20
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Publication No.: US10202623B2Publication Date: 2019-02-12
- Inventor: Masahiro Furutani , Akihiro Uenishi , Koichiro Iwasa
- Applicant: SEKISUI CHEMICAL CO., LTD.
- Applicant Address: JP Osaka
- Assignee: SEKISUI CHEMICAL CO., LTD.
- Current Assignee: SEKISUI CHEMICAL CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2013-008810 20130121
- International Application: PCT/JP2014/050998 WO 20140120
- International Announcement: WO2014/112627 WO 20140724
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P7/18 ; C12N9/10 ; C12N9/02 ; C12N9/88 ; C12N9/00 ; C12N9/04

Abstract:
An object of the present invention is to provide a series of techniques for producing 1,4-butanediol from methanol or the like. Provided is a recombinant cell prepared by introducing a gene encoding at least one enzyme selected from the group consisting of succinate semialdehyde dehydrogenase, succinyl-CoA synthase, CoA-dependent succinate semialdehyde dehydrogenase, 4-hydroxybutyrate dehydrogenase, 4-hydroxybutyryl-CoA transferase, 4-hydroxybutyryl-CoA reductase, 4-hydroxybutyraldehyde dehydrogenase, and alcohol dehydrogenase, into a host cell which is a methylotroph, wherein the gene is expressed in the host cell, and the recombinant cell is capable of producing 1,4-butanediol from at least one C1 compound selected from the group consisting of methane, methanol, methylamine, formic acid, formaldehyde, and formamide.
Public/Granted literature
- US20150368677A1 RECOMBINANT CELL, AND METHOD FOR PRODUCING 1,4-BUTANEDIOL Public/Granted day:2015-12-24
Information query
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