A fluid connector includes first and second clamping arms coupled together for movement between an open condition and a closed, clamping condition for clamping an end of a length of flexible tubing to a fluid fitting. The first and second clamping arms each have a curved interior surface and at least one barb on each curved interior surface. The barbs are configured to engage the exterior surface of the flexible tubing when the first and second clamping arms are in the closed, clamping condition to form a fluid tight connection between the fluid fitting and the flexible tubing. A fluid system and method of fluid connection using the fluid connector are also disclosed.