Invention Grant
- Patent Title: Methods and materials for identifying and treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation
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Application No.: US15456146Application Date: 2017-03-10
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Publication No.: US10203330B2Publication Date: 2019-02-12
- Inventor: Farhad Kosari , George Vasmatzis , Marie-Christine Aubry , Cristiane M. Ida
- Applicant: Mayo Foundation for Medical Education and Research
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Fish & Richardson, P.C.
- Main IPC: C12Q1/6886
- IPC: C12Q1/6886 ; G01N33/574 ; A61K31/13 ; A61K31/198 ; A61K31/225 ; A61K31/26 ; A61K31/404 ; A61K31/428 ; A61K31/44 ; A61K31/4439 ; A61K31/47 ; A61K31/4709 ; A61K31/5025 ; A61K31/506 ; A61K31/517 ; A61K31/7135 ; A61K38/48

Abstract:
This document provides methods and materials involved in identifying mammals having lung adenocarcinoma characterized by neuroendocrine differentiation as well as methods and materials involved in treating mammals having lung adenocarcinoma characterized by neuroendocrine differentiation. For example, methods and materials for using ASCL1 and RET expression levels to identify lung cancer patients having lung adenocarcinoma characterized by neuroendocrine differentiation are provided.
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