The disclosure discloses a liquid crystal display device and a compensation circuit of an organic light emitting diode thereof. The compensation circuit at least includes: a first switch unit, a second switch unit, a third switch unit and a fourth switch unit, when the first switch unit is off, the second switch unit, the third switch unit and the fourth switch unit are on, the compensation circuit drives the organic light-emitting diode to irradiate, in order to compensate the organic light-emitting diode. By the manner above, the disclosure can prevent influence of drift of the threshold voltage of the thin film transistor on the current passing through the organic light-emitting diode.