Invention Grant
- Patent Title: Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases
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Application No.: US14686117Application Date: 2015-04-14
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Publication No.: US10206877B2Publication Date: 2019-02-19
- Inventor: Brian Dean Phenix , Laurent Jean-Claude Bagnol , Geoffrey Glen Brodeur , Sachin Chandran , Eleni Dokou , Lori Ann Ferris , Dragutin Knezic , Katie Lynn McCarty , Ales Medek , Sara A. Waggener
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K45/06 ; A61K9/20 ; A61K31/404 ; A61K31/47 ; C07D215/00 ; C07D209/04 ; C07D215/56 ; C07D405/12 ; A61K31/443 ; A61K31/4709 ; A61K31/4725
Abstract:
The present invention features compositions comprising a plurality of therapeutic agents wherein the presence of one therapeutic agent enhances the properties of at least one other therapeutic agent. In one embodiment, the therapeutic agents are cystic fibrosis transmembrane conductance regulators (CFTR) such as a CFTR corrector or CFTR potentiator for the treatment of CFTR mediated diseases such as cystic fibrosis. Methods and kits thereof are also disclosed.
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