Invention Grant
- Patent Title: Gadolinium-based contrast agents for sensitive detection of Zn2+ with MRI
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Application No.: US15126632Application Date: 2015-03-11
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Publication No.: US10207013B2Publication Date: 2019-02-19
- Inventor: Christian Preihs , Jing Yu , Veronica Clavijo Jordan , Yunkou Wu , Khaled Nasr , A. Dean Sherry , Sara Chirayil
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas Systems
- Current Assignee: The Board of Regents of the University of Texas Systems
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- International Application: PCT/US2015/019928 WO 20150311
- International Announcement: WO2015/142583 WO 20150924
- Main IPC: A61K49/10
- IPC: A61K49/10 ; C07D213/38 ; A61B5/055

Abstract:
In some aspects, the present disclosure provides novel ligands, which may be used to make novel MRI contrast agents for the detection of zinc. In further aspects, by the present disclosure also provides methods of using as imaging agents and compositions thereof.
Public/Granted literature
- US20170106103A1 NEW GADOLINIUM-BASED CONTRAST AGENTS FOR SENSITIVE DETECTION OF Zn2+ WITH MRI Public/Granted day:2017-04-20
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