The invention relates to a cartridge for preparing a beverage, such as coffee, that comprises a hollow member for containing a dose of, for example, ground coffee, said hollow member comprising a side wall, an upper face and a lower face including an extraction membrane, said cartridge being characterized in that it further comprises several separate protrusions provided on said side wall and/or said upper wall, each protrusion including at least one perforation area. The invention also relates to a device for using said cartridge.