Invention Grant
- Patent Title: Isoindoline compositions and methods for treating neurodegenerative disease
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Application No.: US15700923Application Date: 2017-09-11
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Publication No.: US10207991B2Publication Date: 2019-02-19
- Inventor: Gilbert M. Rishton , Susan M. Catalano , Gary C. Look
- Applicant: Cognition Therapeutics, Inc.
- Applicant Address: US PA Pittsburgh
- Assignee: COGNITION THERAPEUTICS, INC.
- Current Assignee: COGNITION THERAPEUTICS, INC.
- Current Assignee Address: US PA Pittsburgh
- Agency: Pepper Hamilton LLP
- Main IPC: C07D209/44
- IPC: C07D209/44 ; C07D491/056 ; A61K31/4035 ; C07D403/06 ; C07D491/048 ; C07D209/62
Abstract:
Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.
Public/Granted literature
- US20180086703A1 ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE Public/Granted day:2018-03-29
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