Invention Grant
- Patent Title: Tertiary alcohol imidazopyrazine BTK inhibitors
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Application No.: US15538910Application Date: 2015-12-17
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Publication No.: US10208047B2Publication Date: 2019-02-19
- Inventor: Jian Liu , Joseph A. Kozlowski , Brian M. Andresen , Sobhana Babu Boga , Xiaolei Gao , Deodial Guy Guiadeen , Jiaqiang Cai , Shilan Liu , Dahai Wang , Hao Wu , Chundao Yang
- Applicant: Jian Liu , Joseph A. Kozlowski , Brian M. Andresen , Sobhana Babu Boga , Xiaolei Gao , Deodial Guy Guiadeen , Jiaqiang Cai , Shilan Liu , Dahai Wang , Hao Wu , Chundao Yang
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Matthew A. Leff; Laura M. Ginkel
- Priority: WOPCT/CN2014/095764 20141231
- International Application: PCT/US2015/066233 WO 20151217
- International Announcement: WO2016/109222 WO 20160707
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/4985 ; A61K45/06
Abstract:
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I, or pharmaceutically acceptable salts thereof, Formula I or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.
Public/Granted literature
- US20170342076A1 TERTIARY ALCOHOL IMIDAZOPYRAZINE BTK INHIBITORS Public/Granted day:2017-11-30
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