Invention Grant
- Patent Title: Process for the preparation of macrocyclic ketone analogs of halichondrin B or pharmaceutically acceptable salts and intermediates thereof
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Application No.: US15510077Application Date: 2015-09-09
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Publication No.: US10208058B2Publication Date: 2019-02-19
- Inventor: Dharmaraj Ramachandra Rao , Geena Malhotra , Venkata Srinivas Pullela , Vinod Parameshwaran Acharya , Nagarjuna Reddy Vantadou
- Applicant: CIPLA LIMITED
- Applicant Address: IN Mumbai
- Assignee: CIPLA LIMITED
- Current Assignee: CIPLA LIMITED
- Current Assignee Address: IN Mumbai
- Agency: Kramer Amado, P.C.
- Priority: IN2869/MUM/2014 20140909
- International Application: PCT/IN2015/000354 WO 20150909
- International Announcement: WO2016/038624 WO 20160317
- Main IPC: C07D407/14
- IPC: C07D407/14 ; C07D493/22 ; C07F7/18 ; C07D519/00

Abstract:
The present invention discloses a novel process for the preparation of macrocyclic ketone analogs of halichondrin B or pharmaceutically acceptable salts thereof and to novel intermediates which are produced during the course of carrying out the novel process.
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