Invention Grant
- Patent Title: CD82-positive cardiac progenitor cells
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Application No.: US15308147Application Date: 2015-04-16
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Publication No.: US10208287B2Publication Date: 2019-02-19
- Inventor: Jun Yamashita , Masafumi Takeda
- Applicant: iHeart Japan Corporation
- Applicant Address: JP Kyoto-shi, Kyoto
- Assignee: iHeart Japan Corporation
- Current Assignee: iHeart Japan Corporation
- Current Assignee Address: JP Kyoto-shi, Kyoto
- Agency: Occhiuti & Rohlicek LLP
- Priority: JP2014-094775 20140501
- International Application: PCT/JP2015/002107 WO 20150416
- International Announcement: WO2015/166638 WO 20151105
- Main IPC: C12N5/077
- IPC: C12N5/077 ; C12N5/10 ; A61K35/12

Abstract:
An object of the present invention is to provide a myocardial progenitor cell that is specifically induced to differentiate into a cardiomyocyte, and a method for preparing the myocardial progenitor cell. A method for preparing a CD82-positive cell includes, in sequence, a step (a) of obtaining stem cells, a step (b) of subjecting the stem cells to induction treatment of differentiation into cardiovascular cells, and a step (c) of separating, from the stem cells having been subjected to the induction treatment of differentiation in the step (b), a CD82-positive cell being negative for at least one cell surface marker selected from CD73, CD44, CD105, CD121a, CD18, and CD120a. This method enables preparation of a CD82-positive cell for use as a myocardial progenitor cell.
Public/Granted literature
- US20170067023A1 CD82-POSITIVE CARDIAC PROGENITOR CELLS Public/Granted day:2017-03-09
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