Invention Grant
- Patent Title: Method for generating high-titer hepatitis E virus stocks and titration assay for hepatitis E virus
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Application No.: US15213766Application Date: 2016-07-19
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Publication No.: US10208291B2Publication Date: 2019-02-19
- Inventor: Brett Buno , Terri Journigan , Joann Hotta , Michael Burdick
- Applicant: GRIFOLS, S.A.
- Applicant Address: ES Barcelona
- Assignee: GRIFOLS, S.A.
- Current Assignee: GRIFOLS, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12Q1/70 ; G01N33/576 ; C12N5/00
Abstract:
Polybrene as an additive in cell culture medium is used in methods for the generation of high-titer hepatitis E virus stocks and assays for titration of hepatitis E virus. A cell culture medium containing polybrene is used for high-titer HEV generation, a method for determining the presence and/or the level of HEV in a sample, and an HEV titration assay using polybrene.
Public/Granted literature
- US20170022481A1 METHOD FOR GENERATING HIGH-TITER HEPATITIS E VIRUS STOCKS AND TITRATION ASSAY FOR HEPATITIS E VIRUS Public/Granted day:2017-01-26
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