A central access control system (10) includes a plurality of doors (44), a plurality of door locks (20) respectively mounted to the doors (44), a control device (33) connected to the door locks (20), and an unlocking device (40) for setting the control device (33) to be in an enabling state or a forbidding state. When the control device (33) is set to be in the forbidding state, the control device (33) outputs a forbidding signal to all of the door locks (20) to set the door locks (20) in a locking state. When the control device (33) is set to be in the enabling mode, the control module (33) outputs an enabling signal to all of the door locks (20), and a locking state or an unlocked state of a locking mechanism (24) of each door lock (20) remains unchanged.