Invention Grant
- Patent Title: Lipoprotein nanoplatelets: fluorescent, zwitterionic probes for molecular and cellular imaging
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Application No.: US15244026Application Date: 2016-08-23
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Publication No.: US10209258B2Publication Date: 2019-02-19
- Inventor: Andrew Smith , Sung Jun Lim , Aditi Das
- Applicant: The Board of Trustees of the University of Illinois
- Applicant Address: US IL Urbana
- Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee Address: US IL Urbana
- Agency: Dilworth IP, LLC
- Main IPC: A61K49/00
- IPC: A61K49/00 ; G01N33/50 ; G01N33/58

Abstract:
Compositions are provided comprising water-stable semi-conductor nanoplatelets encapsulated in a hydrophilic coating further comprising lipids and lipoproteins. Uses include biomolecular imaging and sensing, and methods of making comprise: colloidal synthesis of CdSe core NPLs; layer-by-layer growth of a CdS shell; and encapsulation of CdSe/CdScore/shell NPLs in lipid and lipoprotein components through an evaporation-encapsulation using zwitterionic phospholipids, detergents, and amphipathic membrane scaffold proteins.
Public/Granted literature
- US20170059575A1 LIPOPROTEIN NANOPLATELETS: FLUORESCENT, ZWITTERIONIC PROBES FOR MOLECULAR AND CELLULAR IMAGING Public/Granted day:2017-03-02
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