Invention Grant
- Patent Title: Compositions and methods of diazeniumdiolate-based prodrugs for treating cancer
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Application No.: US15523670Application Date: 2015-11-06
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Publication No.: US10213445B2Publication Date: 2019-02-26
- Inventor: Katrina M. Miranda , David A. Wink , Debashree Basudhar
- Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA , The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Applicant Address: US AZ Tucson US MD Bethesda
- Assignee: Arizona Board of Regents on Behalf of the University of Arizona, a body corporate,The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee: Arizona Board of Regents on Behalf of the University of Arizona, a body corporate,The United States of America as Represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US AZ Tucson US MD Bethesda
- Agency: Hamilton DeSanctis & Cha, LLP
- Agent Don D. Cha
- International Application: PCT/US2015/059428 WO 20151106
- International Announcement: WO2016/073835 WO 20160512
- Main IPC: A61K31/655
- IPC: A61K31/655 ; A61K47/54 ; A61K47/55 ; A61K31/138

Abstract:
The present disclosure provides methods utilizing the diazeniumdiolate-based prodrugs for the treatment of cancer via various mechanisms and procedures. The disclosure also provides kits comprising the diazeniumdiolate-based prodrugs.
Public/Granted literature
- US20170333456A1 Compositions and Methods of Diazeniumdiolate-based Prodrugs for Treating Cancer Public/Granted day:2017-11-23
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