Invention Grant
- Patent Title: Hedgehog antagonists having zinc binding moieties
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Application No.: US15629081Application Date: 2017-06-21
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Publication No.: US10214514B2Publication Date: 2019-02-26
- Inventor: Xiong Cai , Changgeng Qian , Haixiao Zhai
- Applicant: Curis, Inc. , GENENTECH, INC.
- Applicant Address: US MA Lexington US CA South San Francisco
- Assignee: Curis, Inc.,Genentech, Inc.
- Current Assignee: Curis, Inc.,Genentech, Inc.
- Current Assignee Address: US MA Lexington US CA South San Francisco
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar Harlan; Carolyn Elmore
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D401/12 ; C07D239/26 ; C07D213/16 ; C07D235/18 ; C07D403/12 ; C07D213/56 ; C07D239/42 ; C07D213/82
Abstract:
The present invention provides compounds which antagonize hedgehog signaling and inhibit HDAC activity. The compounds can be used in methods of treating proliferative diseases and disorders such as cancer.
Public/Granted literature
- US20170349573A1 HEDGEHOG ANTAGONISTS HAVING ZINC BINDING MOIETIES Public/Granted day:2017-12-07
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