Invention Grant
- Patent Title: Substituted amino triazoles, and methods using same
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Application No.: US15037090Application Date: 2014-12-19
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Publication No.: US10214531B2Publication Date: 2019-02-26
- Inventor: Michael L. Corman , William M. Hungerford , Adam Golebiowski , Raymond P. Beckett , Marzena Mazur , Sylwia Olejniczak , Jacek Olczak
- Applicant: Institute for Drug Discovery, LLC
- Applicant Address: US CT Guilford
- Assignee: Institute for Drug Discovery, LLC
- Current Assignee: Institute for Drug Discovery, LLC
- Current Assignee Address: US CT Guilford
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Kathryn Doyle; Domingos J. Silva
- International Application: PCT/US2014/071490 WO 20141219
- International Announcement: WO2015/095701 WO 20150625
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D401/04 ; C07D487/04 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D249/14 ; C07D471/04 ; C07D405/12
Abstract:
The invention provides novel substituted amino triazoles of Formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, as well as pharmaceutical compositions comprising the same. The compounds of the invention are inhibitors of acidic mammalian chitinase (AMCase) and are useful, in a non-limiting embodiment, for treating asthma. The invention further provides methods of using compounds and/or compositions of the invention to treat asthma and/or to monitor asthma treatment.
Public/Granted literature
- US20160297823A1 SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME Public/Granted day:2016-10-13
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