Invention Grant
- Patent Title: Hydroxmethyl piperidine orexin receptor antagonists
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Application No.: US15529776Application Date: 2015-11-30
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Publication No.: US10214535B2Publication Date: 2019-02-26
- Inventor: Scott D. Kuduk , Nigel Liverton , Yunfu Luo
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- Priority: WOPCT/CN2014/092805 20141202
- International Application: PCT/US2015/062889 WO 20151130
- International Announcement: WO2016/089722 WO 20160609
- Main IPC: C07D491/048
- IPC: C07D491/048 ; C07D401/14 ; A61K45/06 ; A61K31/4545 ; C07D401/10 ; C07D401/12
Abstract:
The present invention is directed to hydroxymethyl piperidine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20170320884A1 HYDROXMETHYL PIPERIDINE OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2017-11-09
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