Invention Grant
- Patent Title: Btk inhibitors
-
Application No.: US15538971Application Date: 2015-12-17
-
Publication No.: US10214546B2Publication Date: 2019-02-26
- Inventor: Jian Liu , Joseph A. Kozlowski , Sobhana Babu Boga , Xiaolei Gao , Deodial Guy Guiadeen , Jiaqiang Cai , Shilan Liu , Dahai Wang , Hao Wu , Chundao Yang
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Matthew A. Leff; Laura M. Ginkel
- Priority: WOPCT/CN2014/095769 20141231
- International Application: PCT/US2015/066219 WO 20151217
- International Announcement: WO2016/109216 WO 20160707
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61K45/06 ; A61K31/4985 ; A61P19/02

Abstract:
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders.
Public/Granted literature
- US20180118766A1 BTK INHIBITORS Public/Granted day:2018-05-03
Information query