Invention Grant
- Patent Title: Protein assay method specific to TRACP-5b (tartrate resistant acid phosphatase 5b)
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Application No.: US15505762Application Date: 2015-08-07
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Publication No.: US10214592B2Publication Date: 2019-02-26
- Inventor: Wataru Kikuchi , Kumiko Sasagawa , Kenta Noda
- Applicant: NITTO BOSEKI CO., LTD.
- Applicant Address: JP Fukushima-shi
- Assignee: NITTO BOSEKI CO., LTD.
- Current Assignee: NITTO BOSEKI CO., LTD.
- Current Assignee Address: JP Fukushima-shi
- Agency: Kratz, Quintos & Hanson, LLP
- Priority: JP2014-168934 20140822
- International Application: PCT/JP2015/072468 WO 20150807
- International Announcement: WO2016/027697 WO 20160225
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C12Q1/00 ; C12N5/07 ; C12N5/16 ; C07K16/40 ; C12N15/00 ; C12N15/02 ; G01N33/53 ; G01N33/543 ; G01N33/545 ; G01N33/553 ; G01N33/577 ; G01N33/573 ; C12N5/12 ; C07K16/18 ; A61K39/00 ; G01N33/50 ; C07K16/30 ; A61K38/00 ; C12N9/16
Abstract:
The purpose of the present invention is to provide a monoclonal antibody that is useful in specifically assaying tartrate resistant acid phosphatase 5b (TRACP-5b). A hybridoma producing a monoclonal antibody against TRACP-5b, said monoclonal antibody showing higher reactivity with TRACP-5b than with tartrate resistant acid phosphatase 5a (TRACP-5a) and, therefore, being specific to TRACP-5b, is obtained by cell fusion using, as an antigen, human recombinant TRACP-5b purified from silkworm silk gland. By using this monoclonal antibody, TRACP-5b in a specimen can be highly sensitively and specifically detected.
Public/Granted literature
- US20170267782A1 PROTEIN ASSAY METHOD SPECIFIC TO TRACP-5b (TARTRATE RESISTANT ACID PHOSPHATASE 5b) Public/Granted day:2017-09-21
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