Invention Grant
- Patent Title: Colorectal cancer drug, and method for predicting prognosis of colorectal cancer patient
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Application No.: US15123621Application Date: 2015-03-04
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Publication No.: US10214743B2Publication Date: 2019-02-26
- Inventor: Hirofumi Yamamoto , Masaki Mori , Yuichiro Doki , Junichi Nishimura
- Applicant: Hirofumi Yamamoto , Masaki Mori
- Applicant Address: JP Suita-shi, Osaka JP Suita-shi, Osaka
- Assignee: Hirofumi Yamamoto,Masaki Mori
- Current Assignee: Hirofumi Yamamoto,Masaki Mori
- Current Assignee Address: JP Suita-shi, Osaka JP Suita-shi, Osaka
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: JP2014-041768 20140304
- International Application: PCT/JP2015/056354 WO 20150304
- International Announcement: WO2015/133522 WO 20150911
- Main IPC: A61K31/7088
- IPC: A61K31/7088 ; C12N15/11 ; C12N15/113 ; A61K47/02 ; A61K31/7105 ; C12Q1/6886 ; A61K47/48 ; A61K9/00 ; A61K9/51
Abstract:
The purpose of the present invention is to provide a colorectal cancer drug that uses microRNA exhibiting outstanding effectiveness in colorectal cancer patients, particularly colorectal cancer patients having a mutated KRAS gene. miR4689 and/or miR4685-3p can suppress the growth of colorectal cancer cells, particularly colorectal cancer cells having a mutated KRAS gene, and thus exhibit an effective antitumor effect.
Public/Granted literature
- US20170073686A1 COLORECTAL CANCER DRUG, AND METHOD FOR PREDICTING PROGNOSIS OF COLORECTAL CANCER PATIENT Public/Granted day:2017-03-16
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