Invention Grant
- Patent Title: Treatment of brain derived neurotrophic factor (BDNF) related diseases by inhibition of natural antisense transcript to BDNF
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Application No.: US15398630Application Date: 2017-01-04
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Publication No.: US10214745B2Publication Date: 2019-02-26
- Inventor: Mohammad Ali Faghihi , Carlos Coito
- Applicant: The Scripps Research Institute , Curna, Inc.
- Applicant Address: US CA La Jolla US FL Miami
- Assignee: The Scripps Research Institute,Curna, Inc.
- Current Assignee: The Scripps Research Institute,Curna, Inc.
- Current Assignee Address: US CA La Jolla US FL Miami
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/113
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Brain derived neurotrophic factor (BDNF), in particular, by targeting natural antisense polynucleotides of Brain derived neurotrophic factor (BDNF). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of BDNF.
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