A method for operating an internal combustion engine is presented in which a noise characteristic value, which is representative of a measurement of a noise of the measurement signal of a respective exhaust gas probe, is determined as a function of a profile of the measurement signal of the respective exhaust gas probe. A pressure characteristic value, which is assigned to a respective cylinder, is determined as a function of a profile of a measurement signal of a crankshaft angle sensor and a profile of a pressure measurement signal of a cylinder pressure sensor. Respective actuation signals for actuating respective injection valves are adapted as a function of the pressure characteristic value and the noise characteristic value assigned to the respective cylinder, for the purpose of approximating an air/fuel ratio in the individual cylinders.