Provided are an OLED display device drive system and an OLED display device drive method. The OLED display device drive system introduces the common voltage signal (Vcm) in the threshold voltage detection circuit (2) into the sub pixel driving circuit (1), and in the writing stage, by applying the common voltage signal (Vcm) to the organic light emitting diode (D1), the organic light emitting diode is in the negative voltage and reverse biased, and then in the light emitting stage, the common voltage signal (Vcm) is removed from the organic light emitting diode (D1), and then the trans-voltage of the organic light emitting diode (D1) changes from the negative voltage to the positive voltage and the light is normally emitted. Thus, the organic light emitting diode (D1) has been through the positive and negative alternating current drive, and can delay the aging of the OLED and extend the OLED lifetime.