A gastrointestinal (GI) sensor deployment device is disclosed. In implementations, the sensor deployment device includes an orally-administrable capsule with a tissue capture device removably coupled to the orally-administrable capsule. The tissue capture device includes a plurality of fasteners for connecting the tissue capture device to GI tissue within a body. A biometric sensor is coupled to the tissue capture device for continuous or periodic monitoring of the GI tract of the body at the GI tissue attachment location. A chamber within the orally-administrable capsule is configured to draw gastrointestinal tissue towards the plurality of fasteners when a fluid pressure of the chamber is increased. An actuator can be configured to cause an increase of the fluid pressure of the chamber. Control circuitry coupled to the actuator can be configured to trigger the actuator to cause the increase of the fluid pressure of the chamber at a selected time.