Invention Grant
- Patent Title: Method of treating pleural abnormality
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Application No.: US14805877Application Date: 2015-07-22
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Publication No.: US10219794B2Publication Date: 2019-03-05
- Inventor: Tai-Horng Young , Jin-Shing Chen , Hong-Shiee Lai , Ke-Cheng Chen , Ya-Shuan Chou , Yong-Chong Lin , Hao-Ying Hsieh , Hsu-Hsien Chang
- Applicant: National Taiwan University
- Applicant Address: TW Taipei
- Assignee: National Taiwan University
- Current Assignee: National Taiwan University
- Current Assignee Address: TW Taipei
- Agent Hannah M. Tien
- Priority: TW103125198A 20140722
- Main IPC: A61L31/06
- IPC: A61L31/06 ; A61L31/04 ; A61B17/00 ; A61L27/18 ; A61L27/54 ; A61L27/56 ; A61L27/58 ; A61F2/00

Abstract:
The invention relates to a method of treating pleural abnormalities in a subject in need thereof, comprising the steps of: (a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. The present invention also relates to a biodegradable adhesion membrane used for treating pleural abnormalities, comprising: a biodegradable base material selected from the group consisting of polycaprolactone (PCL), polylactic acid or polylactide (PLA), polyhydroxybutyrate (PHB), poly(ethylene adipate), poly(butylene adipate) (PBA), chitosan, hyaluronic acid, and polyglycolic acid (PGA); wherein the thickness of the membrane is 0.1-1 mm.
Public/Granted literature
- US20160022878A1 METHOD OF TREATING PLEURAL ABNORMALITY Public/Granted day:2016-01-28
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