Invention Grant
- Patent Title: FXR (NR1H4) binding and activity modulating compounds
-
Application No.: US15783530Application Date: 2017-10-13
-
Publication No.: US10220027B2Publication Date: 2019-03-05
- Inventor: Olaf Kinzel , Christoph Steeneck , Claus Kremoser
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: GILEAD SCIENCES, INC.
- Current Assignee: GILEAD SCIENCES, INC.
- Current Assignee Address: US CA Foster City
- Agency: Sheppard Mullin Richter & Hampton LLP
- Priority: EP11005722 20110713
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/42 ; A61K31/422 ; C07D261/08 ; C07D413/12 ; C07D413/14
Abstract:
The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
Public/Granted literature
- US20180200243A1 Novel FXR (NR1H4) binding and activity modulating compounds Public/Granted day:2018-07-19
Information query
IPC分类:
