Invention Grant
- Patent Title: Hepatitis B viral assembly effectors
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Application No.: US15030378Application Date: 2014-10-16
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Publication No.: US10220034B2Publication Date: 2019-03-05
- Inventor: Adam Zlotnick , Lichun Li , William W. Turner, Jr. , Samson Francis
- Applicant: Indiana University Research and Technology Corp.
- Applicant Address: US IN Indianapolis
- Assignee: Indiana University Research and Technology Corporation
- Current Assignee: Indiana University Research and Technology Corporation
- Current Assignee Address: US IN Indianapolis
- Agency: Faegre Baker Daniels LLP
- International Application: PCT/US2014/060869 WO 20141016
- International Announcement: WO2015/057945 WO 20150423
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D239/47 ; C07D239/48
Abstract:
Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.
Public/Granted literature
- US20160271130A1 HEPATITIS B VIRAL ASSEMBLY EFFECTORS Public/Granted day:2016-09-22
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