In the method for manufacturing a three-dimensional structure of the invention, an ink for forming an entity portion is applied to a region where the three-dimensional structure is configured, and an ink for forming a sacrificial layer is applied to a region on a surface side of an outermost layer which is adjacent to a region to become the outermost. As the ink for forming a sacrificial layer, a first ink for forming a sacrificial layer and a second ink for forming a sacrificial layer are used. At the time of curing the ink for forming an entity portion, the viscoelasticity of the first ink is smaller than that of the ink for forming an entity portion, and at the time of curing the ink for forming an entity portion, the viscoelasticity of the second ink is greater than that of the ink for forming an entity portion.