Invention Grant
- Patent Title: Inhibitors of plasma kallikrein
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Application No.: US14907842Application Date: 2014-08-14
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Publication No.: US10221161B2Publication Date: 2019-03-05
- Inventor: Hannah Joy Edwards , David Michael Evans , Premji Meghani , Andrew Richard Novak
- Applicant: Kalvista Pharmaceuticals Limited
- Applicant Address: GB Salisbury, England
- Assignee: Kalvista Pharmaceuticals Limited
- Current Assignee: Kalvista Pharmaceuticals Limited
- Current Assignee Address: GB Salisbury, England
- Agency: Baker & Hostetler LLP
- International Application: PCT/GB2014/052510 WO 20140814
- International Announcement: WO2015/022546 WO 20150219
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D413/14 ; C07D401/10 ; C07D401/12 ; C07D403/10 ; C07D403/14 ; C07D417/14 ; C07D471/04

Abstract:
The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.
Public/Granted literature
- US20160168123A1 INHIBITORS OF PLASMA KALLIKREIN Public/Granted day:2016-06-16
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