![Preparation of certain substituted [((6bR,10aS)-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof](/docs/US/2019-03-05/US10221176B2/abs.jpg.600x600.jpg)
- Patent Title: Preparation of certain substituted [((6bR,10aS)-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof
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Application No.: US15660762Application Date: 2017-07-26
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Publication No.: US10221176B2Publication Date: 2019-03-05
- Inventor: John Charles Tomesch , Peng Li , Wei Yao , Qiang Zhang , James David Beard , Andrew S. Thompson , Hua Cheng , Lawrence P. Wennogle
- Applicant: INTRA-CELLULAR THERAPIES, INC.
- Applicant Address: US NY New York
- Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee Address: US NY New York
- Agency: Hoxie & Associates LLC
- Main IPC: C07D471/22
- IPC: C07D471/22 ; C07D487/22 ; C07D471/16 ; C07D471/04
![Preparation of certain substituted [((6bR,10aS)-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines and pharmaceutically acceptable salts thereof](/abs-image/US/2019/03/05/US10221176B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides methods for the preparation of substituted heterocycle fused gamma-carbolines of Formula 2F, as shown below, intermediates useful in producing them and methods for producing such intermediates and such heterocycle fused gamma-carbolines, such methods comprising the preparation of a Compound of Formula 2F, as shown below and as further defined herein:
Public/Granted literature
- US20180044337A1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS Public/Granted day:2018-02-15
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