Invention Grant
- Patent Title: Purine inhibitors of human phosphatidylinositol 3-kinase delta
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Application No.: US15736510Application Date: 2016-06-24
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Publication No.: US10221178B2Publication Date: 2019-03-05
- Inventor: Meredeth Ann McGowan , Hua Zhou , Jason D. Katz , Lihu Yang , Joey L. Methot , Kathryn Ann Lipford , Shimin Xu , Ning Fu , Guoquan Xu , Deqian Bian , Jianmin Fu , Yabin Li , Kin Chiu Fong
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; John C. Todaro
- Priority: CNPCT/CN2015/082673 20150629
- International Application: PCT/US2016/039147 WO 20160624
- International Announcement: WO2017/003836 WO 20170105
- Main IPC: C07D473/30
- IPC: C07D473/30 ; C07D473/34 ; C07D471/04 ; C07D519/00 ; A61K45/06 ; A61P37/00 ; A61P17/06 ; A61P11/06 ; A61P11/08 ; A61P11/00 ; A61P35/00
Abstract:
The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflammation, asthma, COPD and cancer.
Public/Granted literature
- US20180141947A1 Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta Public/Granted day:2018-05-24
Information query
