Invention Grant
- Patent Title: LEDGF peptides and formulations thereof for treatment of degenerative disorders
-
Application No.: US15348970Application Date: 2016-11-10
-
Publication No.: US10221226B2Publication Date: 2019-03-05
- Inventor: Uday B. Kompella , Rinku Baid , Arun K. Upadhyay , Sarath Yandrapu
- Applicant: The Regents of the University of Colorado, a body corporate
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Hamilton DeSanctis & Cha, LLP
- Agent Don D. Cha
- Main IPC: C07K14/475
- IPC: C07K14/475 ; A61K38/18 ; A61K47/52 ; A61K47/69 ; A61K38/00
Abstract:
LEDGF peptides with anti-protein aggregation activity and methods of use are provided. The LEDGF peptides disclosed herein demonstrate an ability to treat degenerative diseases and diseases with various cellular stresses including oxidative stress and protein-aggregation stress. In addition, extended release formulations, including formulations suitable for ophthalmic administration are provided.
Public/Granted literature
- US20170129929A1 LEDGF PEPTIDES AND FORMULATIONS THEREOF FOR TREATMENT OF DEGENERATIVE DISORDERS Public/Granted day:2017-05-11
Information query
