Invention Grant
- Patent Title: In vitro model for a tumor microenvironment
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Application No.: US15483010Application Date: 2017-04-10
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Publication No.: US10221394B2Publication Date: 2019-03-05
- Inventor: Brian R. Wamhoff , Brett R. Blackman , Robert A. Figler , Daniel G. Gioeli , Michael B. Simmers
- Applicant: HemoShear, LLC
- Applicant Address: US VA Charlottesville
- Assignee: HemoShear, LLC
- Current Assignee: HemoShear, LLC
- Current Assignee Address: US VA Charlottesville
- Agency: Stinson Leonard Street LLP
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; C12N5/09 ; C12N5/071
Abstract:
Methods for mimicking a tumor microenvironment in vitro are provided. The methods comprise indirectly applying a shear stress upon at least one tumor cell type plated on a surface within a cell culture container. Methods for mimicking tumor metastasis and methods for testing drugs or compounds in such systems are also provided.
Public/Granted literature
- US20180016557A1 IN VITRO MODEL FOR A TUMOR MICROENVIRONMENT Public/Granted day:2018-01-18
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