Invention Grant
- Patent Title: Method of gene expression regulation
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Application No.: US15891504Application Date: 2018-02-08
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Publication No.: US10221423B2Publication Date: 2019-03-05
- Inventor: Long Liu , Jian Chen , Guocheng Du , Xian Yin , Jianghua Li
- Applicant: Jiangnan University
- Applicant Address: CN Wuxi
- Assignee: Jiangnan University
- Current Assignee: Jiangnan University
- Current Assignee Address: CN Wuxi
- Agency: SZDC Law P.C.
- Priority: CN201510812316 20151120
- Main IPC: C12N15/80
- IPC: C12N15/80 ; C12N1/14 ; C07K14/38 ; C12N15/63

Abstract:
The invention discloses a promoter which can be induced to express in acidic conditions, and relates to the field of bioengineering technology. The promoters of the invention are separated from A. niger and can actuate and/or regulate the expression of the effectively connected nucleic acids in A. niger. In the invention the expression of the promoters is studied in A. niger, and it is indicated that some promoters show weak expression, and some show strong activity. The invention provides an effective method and new thought for organic acids production by fungi or other products produced by fermentation under acidic conditions.
Public/Granted literature
- US20180171344A1 METHOD OF GENE EXPRESSION REGULATION Public/Granted day:2018-06-21
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