- Patent Title: Gene capable of enhancing salicylic acid-induced cell death in a plant cell and contributing to resistance to the fungal virulence factor deoxynivalenol, resistance to fusarium fungi and fusarium head blight disease, and a recombinant construct including the gene
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Application No.: US15325948Application Date: 2015-07-15
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Publication No.: US10221427B2Publication Date: 2019-03-05
- Inventor: Fiona Doohan , Guillaume Erard , Alexandre Perochon , Khairul Ansari , Arunachalam Chanemougasoundharam , Joanna Kacprzyk
- Applicant: University College Dublin, National University of Ireland, Dublin
- Applicant Address: IE Dublin
- Assignee: University College Dublin, National University of Ireland, Dublin
- Current Assignee: University College Dublin, National University of Ireland, Dublin
- Current Assignee Address: IE Dublin
- Agency: Cesari and McKenna, LLP
- Priority: EP14177179 20140715
- International Application: PCT/EP2015/066197 WO 20150715
- International Announcement: WO2016/008942 WO 20160121
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C07K14/415

Abstract:
The Applicant has identified a novel DON-responsive orphan gene (ENST1—SEQ ID NO: 1), and its promoter, which features DON-responsive elements, which can be used to drive the expression of FHB resistance genes. The Applicant has isolated two variants of the gene from wheat that share approximately 94% homology with ENST1. The Applicant has shown that this gene has homologs of >62% nucleotide sequence identity exist in Aegilops tauschii, Brachypodium distachyon, Festuca pratensis, Hordeum vulgare and Triticum aestivum.
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