The present invention relates to a method and an apparatus for beamforming by a base station in a wireless communication system supporting multiple antennas. Particularly, the method comprises the steps of: determining a first coverage on the basis of long-term feedback information; setting multiple logical antenna ports for the first coverage on the basis of a combination of multiple horizontal beams and multiple vertical beams; and transmitting a channel state information-reference signal to a terminal according to a precoding matrix index which is set on the basis of the multiple antenna ports, wherein the multiple horizontal beams respectively correspond to multiple second coverages divided into horizontal domains on the basis of the first coverage, and the multiple vertical beams respectively correspond to multiple third coverages divided into vertical domains on the basis of the first coverage.