Invention Grant
- Patent Title: PRMT1 inhibitors and uses thereof
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Application No.: US15850367Application Date: 2017-12-21
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Publication No.: US10227307B2Publication Date: 2019-03-12
- Inventor: Kevin Wayne Kuntz , Lorna Helen Mitchell , Gideon Shapiro , Richard Chesworth , Paula Ann Boriack-Sjodin
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07D231/12
- IPC: C07D231/12 ; A61K31/415
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.
Public/Granted literature
- US20180265478A1 PRMT1 INHIBITORS AND USES THEREOF Public/Granted day:2018-09-20
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