A lockout device configured to prevent access to a pipe flange connection comprises a bar, a pair of opposed cup sections, and an engagement mechanism. The pair of opposed cup sections may each include a main cup segment coupled to the bar and a hinged cup segment hingedly coupled to the main cup segment. One or more of the main cup segments can be slidably coupled to the bar and the engagement mechanism can be configured to selectively prevent the main cup segments(s) that is/are slidably coupled to the bar from sliding relative to the bar. This engagement mechanism or latch can be hinged on a side of the bar opposite a side of the bar on which the engagement mechanism includes openings for receiving one or more locks.