A scalpel handle for holding a blade includes a handle member and a finger-operable actuator having a blade shield portion. The actuator is mounted upon the handle member for movement relative thereto between a first condition at which the blade shield portion covers the edge of the blade and a second condition at which the blade shield portion is disposed in out-of-the-way position so that by moving the actuator between the first and second conditions, the blade shield portion is moved between its blade-covering and its out-of-the-way positions. An over center spring is interposed between the actuator and the handle member so that upon movement of the actuator into its second condition, the blade shield portion is biased into the out-of-the-way position and so that upon movement of the actuator into its first condition, the blade shield portion is biased into the blade-covering position.