Invention Grant
- Patent Title: Cyclopropylamine compounds as histone demethylase inhibitors
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Application No.: US15314851Application Date: 2015-05-29
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Publication No.: US10233165B2Publication Date: 2019-03-19
- Inventor: Paola Vianello , Mario Varasi , Ciro Mercurio , Anna Cappa , Giuseppe Meroni , Manuela Villa , Antonello Mai , Sergio Valente
- Applicant: IEO—Instituto Europeo di Oncologia S.r.l.
- Applicant Address: IT Milan
- Assignee: Istituto Europeo di Oncologia S.r.l.
- Current Assignee: Istituto Europeo di Oncologia S.r.l.
- Current Assignee Address: IT Milan
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Thomas J. Paxton
- Priority: EP14170656 20140530; EP14193312 20141114
- International Application: PCT/EP2015/062037 WO 20150529
- International Announcement: WO2015/181380 WO 20151203
- Main IPC: A61K31/421
- IPC: A61K31/421 ; A61K31/445 ; A61K31/495 ; A61K31/5375 ; A61K45/06 ; C07D211/14 ; C07D211/34 ; C07D241/04 ; C07D263/22 ; C07D265/30 ; C07D295/155
Abstract:
The present disclosure relates to cyclopropyl compounds of general formula (I), wherein R1, and R2 are as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.
Public/Granted literature
- US20170190680A1 CYCLOPROPYLAMINE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS Public/Granted day:2017-07-06
Information query
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