Invention Grant
- Patent Title: Compounds, linker-drugs and ligand-drug conjugates
-
Application No.: US15341117Application Date: 2016-11-02
-
Publication No.: US10233212B2Publication Date: 2019-03-19
- Inventor: On Lee , Mei-Hsuan Tsai
- Applicant: Industrial Technology Research Institute
- Applicant Address: TW Hsinchu
- Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- Current Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- Current Assignee Address: TW Hsinchu
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/44 ; C07K7/02 ; A61K47/68 ; C07K5/02 ; A61K47/55

Abstract:
A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), R1, R2 and R3 are each, independently, hydrogen, amino, nitro, halogen, hydroxyl, C1-C6 alkoxy, carboxylic acid, C1-C6 alkoxycarbonyl, C1-C6 amino, C1-C6 aminocarbonyl, C1-C6 alkyl, branched C1-C6 alkyl, C1-C6 cycloalkyl, C1-C6 heterocyclic, aryl or heteroaryl, provided at least one of R1 and R3 is an amino group. A linker-drug and a ligand-drug conjugate including the compound are also provided.
Public/Granted literature
- US20180016300A1 COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES Public/Granted day:2018-01-18
Information query
IPC分类: