- Patent Title: Lipopolysaccharide-targeted peptide mimic vaccine against Q fever
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Application No.: US15195586Application Date: 2016-06-28
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Publication No.: US10233233B2Publication Date: 2019-03-19
- Inventor: Guoquan Zhang
- Applicant: Guoquan Zhang
- Applicant Address: US MO Columbia
- Assignee: The Curators of the University of Missouri
- Current Assignee: The Curators of the University of Missouri
- Current Assignee Address: US MO Columbia
- Agency: Shook, Hardy & Bacon L.L.P.
- Main IPC: C07K7/08
- IPC: C07K7/08 ; A61K39/00 ; C07K16/12
Abstract:
A vaccine and method of vaccination for conferring immunity to Q fever is described. The vaccine comprises a polypeptide with a sequence of SLTWHKHELHRK (SEQ ID NO: 7) (m1E41920) or SPPWHKHELHRK (SEQ ID NO: 8) (m1E44), or at least 90% identity to m1E41920 or m1E44. Constructs are also provided for use in vaccination and treatment of Q fever. A method to identify and generate new vaccines to prevent diseases caused by intracellular Gram-negative bacteria is also described.
Public/Granted literature
- US20160304587A1 Lipopolysaccharide-Targeted Peptide Mimic Vaccine Against Q Fever Public/Granted day:2016-10-20
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